Editor-in-Chief ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope |
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- Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells
The dynamic changes between glycolysis and oxidative phosphorylation (OXPHOS) for adenosine triphosphate (ATP) output, along with glucose, glutamine, and fatty acid utilization, etc., lead to the maintenance and selection of growth advantageous to tumor cell subgroups in an environment of iron starvation and hypoxia.
Read More >> - Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis
Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.
Read More >> - Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis
The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.
Read More >> - Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment
The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.
Read More >> - Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy
Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in outcomes of non-small cell lung cancer (NSCLC).
Read More >>
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Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States | Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line, ICC-X2 | |||
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Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases |
Current Issue |
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Vol. 15, No. 2, Apr 2024
Table of Contents
Review
Pigs: Large Animal Preclinical Cancer Models | Abstract HTML PDF |
Kirtan Joshi, Tejas Katam, Akshata Hegde, Jianlin Cheng, Randall S. Prather, Kristin Whitworth, Kevin Wells, Jeffrey N. Bryan, Timothy Hoffman, Bhanu P. Telugu, Jussuf T. Kaifi, Satyanarayana Rachagani | 149-168 |
doi: https://doi.org/10.14740/wjon1763 |
Original Article
Sphingosine-1-Phosphate Inhibition Increases Endoplasmic Reticulum Stress to Enhance Oxaliplatin Sensitivity in Pancreatic Cancer | Abstract HTML PDF Suppl1 |
Zachary Gao, Harinarayanan Janakiraman, Yang Xiao, Sung Wook Kang, Jiangling Dong, Jasmine Choi, Besim Ogretmen, Hyun-Sung Lee, Ernest Ramsay Camp | 169-180 |
doi: https://doi.org/10.14740/wjon1768 |
Spinster Homologue 2 Expression Correlates With Improved Patient Survival in Hepatocellular Carcinoma Despite Association With Lymph-Angiogenesis | Abstract HTML PDF |
Joy Sarkar, Masanori Oshi, Vikas Satyananda, Kohei Chida, Li Yan, Aparna Maiti, Nitai Hait, Itaru Endo, Kazuaki Takabe | 181-191 |
doi: https://doi.org/10.14740/wjon1732 |
The Combination of Afatinib With Dasatinib or Miransertib Results in Synergistic Growth Inhibition of Stomach Cancer Cells | Abstract HTML PDF |
Tina Al-Janaby, Narmin Nahi, Alan Seddon, Izhar Bagwan, Said Khelwatty, Helmout Modjtahedi | 192-208 |
doi: https://doi.org/10.14740/wjon1769 |
DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 |
You Lin Chen, Yi Liu, Yan Xu, An Qiang Yang, Gui Jie Chen, Jin Shan Xing, Hong Wei Su, Li Shang Liao | 209-222 |
doi: https://doi.org/10.14740/wjon1754 |
Predictors of Immunotherapy Efficacy in Metastatic Non-Small Cell Lung Cancer: Lung Immune Prognostic Index and Immune-Related Toxicity - ARTICLE | Abstract HTML PDF |
Alba Moratiel Pellitero, Maria Zapata Garcia, Marta Gascon Ruiz, Jose Miguel Arbones-Mainar, Rodrigo Lastra del Prado, Dolores Isla | 223-238 |
doi: https://doi.org/10.14740/wjon1790 |
Predictive Factors of Successful Double J Stent Insertion Among Advanced Cervical Cancer Patients | Abstract HTML PDF |
Syah Mirsya Warli, Mohd. Rhiza Z. Tala, William Saputra Wijaya | 239-245 |
doi: https://doi.org/10.14740/wjon1631 |
Association of Lung Cancer Risk With the Presence of Both Lung Nodules and Emphysema in a Lung Cancer Screening Trial | Abstract HTML PDF Suppl1 Suppl2 Suppl3 |
Ya Liu, Zhuo Wei Feng, Xiao Min Liu, Hong Yuan Duan, Zhang Yan Lyu, Yu Bei Huang, Fang Fang Song, Feng Ju Song | 246-256 |
doi: https://doi.org/10.14740/wjon1782 |
High Ki67 Gene Expression Is Associated With Aggressive Phenotype in Hepatocellular Carcinoma | Abstract HTML PDF |
Vicente Ramos-Santillan, Masanori Oshi, Erek Nelson, Itaru Endo, Kazuaki Takabe | 257-267 |
doi: https://doi.org/10.14740/wjon1751 |
Significance of Pretreatment Hemoglobin-Albumin-Lymphocyte-Platelet Index for the Prediction of Suboptimal Surgery in Epithelial Ovarian Cancer | Abstract HTML PDF PDF Suppl2 |
Thiti Atjimakul, Nungrutai Saeaib, Thara Tunthanathip, Paramee Thongsuksai | 268-278 |
doi: https://doi.org/10.14740/wjon1778 |
Incidence of Colorectal Cancer After Intestinal Infection Due to Clostridioides difficile | Abstract HTML PDF |
Raina K. Patel, Matthew Cardeiro, Lexi Frankel, Enoch Kim, Kazuaki Takabe, Omar M. Rashid | 279-286 |
doi: https://doi.org/10.14740/wjon1802 |
Lipid Profiles Impact on the Oncologic Outcome of Upper Tract Urothelial Carcinoma | Abstract HTML PDF |
Kuan-Yi Tu, Ching-Chia Li, Wei-Ming Li, Hsin-Chih Yeh, Hung-Lung Ke, Wen-Jeng Wu, Tsu Ming Chien, Sheng-Chen Wen, Yen-Chun Wang, Hsiang-Ying Lee | 287-297 |
doi: https://doi.org/10.14740/wjon1800 |
Gene Expression Profile-Guided Personalized Intraperitoneal Chemotherapy for Gastric Cancer Peritoneal Carcinomatosis | Abstract HTML PDF |
Vitaly A. Markovich, Sergey A. Tuzikov, Evgeny O. Rodionov, Natalia O. Popova, Matvey M. Tsyganov, Sergey V. Miller, Danil V. Podolko, Irina A. Tsydenova, Marina K. Ibragimova, Nikolai V. Litviakov | 298-308 |
doi: https://doi.org/10.14740/wjon1578 |
Role of Postoperative Radiotherapy on High-Risk Stage pIIIA-N2 Non-Small Cell Lung Cancer Patients After Complete Resection and Adjuvant Chemotherapy: A Retrospective Cohort Study | Abstract HTML PDF |
Zu Yi Chen, Huan Wei Liang, Yang Liu, Wei Huang, Xin Bin Pan | 309-318 |
doi: https://doi.org/10.14740/wjon1832 |
Short Communication
Characterization of Asciminib-Resistant Philadelphia Chromosome-Positive Cells | Abstract HTML PDF |
Seiichi Okabe, Mitsuru Moriyama, Akihiko Gotoh | 319-324 |
doi: https://doi.org/10.14740/wjon1818 |
Study Protocol
Empowerment-Led Guided Self-Help Intervention for Symptom Burden in Breast Cancer Women Treated With Ovarian Function Suppression: A Randomized Trial Protocol | Abstract HTML PDF |
Yuan Li, Yun Yun Chen, Su Xing Wang, Zheng Yue Dai, Jia Song Cui, Yu Fei Xing, Qing Wu, Qiong Fang | 325-336 |
doi: https://doi.org/10.14740/wjon1817 |