- Check out new article collection Research on Genes and Environment by the Malaysian Society of Toxicology
- Updated Aims & Scope: to enhance the quality of Genes and Environment and its contents, the Journal has updated and revised its Aims and Scope.
- Lessons Learned from Japanese Association for Cancer Prevention and Future Opportunities- article collection now complete.
What's new
[Featured Article]
Application of image-recognition techniques to automated micronucleus detection in the in vitro micronucleus assay
Hiromi Yoda, Kazuya Abe, Hideya Takeo, Takeji Takamura-Enya & Ayumi Koike-Takeshita
An in vitro micronucleus assay is a standard genotoxicity test. Although the technique and interpretation of the results are simple, manual counting of the total and micronucleus-containing cells in a microscopic field is tedious. To address this issue, several systems have been developed for quick and efficient micronucleus counting, including flow cytometry and automated detection based on specialized software and detection systems that analyze images.
[Featured Article]
The spectrum of TP53 mutations in Rwandan patients with gastric cancer
Augustin Nzitakera, Jean Bosco Surwumwe, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Delphine Uwamariya, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Belson Rugwizangoga, Yuji Iwashita, Hidetaka Yamada, Kimio Yoshimura, Haruhiko Sugimura & Kazuya Shinmura
Gastric cancer is the sixth most frequently diagnosed cancer and third in causing cancer-related death globally. The most frequently mutated gene in human cancers is TP53, which plays a pivotal role in cancer initiation and progression. In Africa, particularly in Rwanda, data on TP53 mutations are lacking. Therefore, this study intended to obtain TP53 mutation status in Rwandan patients with gastric cancer.
Read this article: Volume 46, Article number: 8 (2024)
Article collections and Special Issues
- Research on Genes and Environment by the Malaysian Society of Toxicology
- Lessons Learned from Japanese Association for Cancer Prevention and Future Opportunities
- Current topics in China for Environmental Mutagen Research
- G&E Best Paper Award collection
- Special Issue in memory of Takashi Sugimura
- Asian Conference on Environmental Mutagens (ACEM2019)
- Article collection: Meeting Reports: collection of various meeting reports published in G&E
- Article collection: Genotoxicity Tests
- JEMS Open Symposia 2017&2018: “Challenges of Young Scientists”
- 10th Anniversary Special Issue
- JEMS Open Symposium 2015: “Life Style and Cancer”
- Asian Conference on Environmental Mutagens (ACEM2014)
About the Editor
Editor-in-Chief
Masami Yamada studied bacterial genetics and got a PhD degree from Osaka University. Since 1990, using genetic engineering techniques, she has constructed many strains from standard tester strains for the Ames test at the National Institute of Health Sciences, Tokyo. Such strains are useful for research fields on environmental mutagens.
Strain requests come to her every year from domestic, Asia, Europe, North America, South America, and other countries. Currently, she teaches Biology and Genetic Engineering at National Defense Academy of Japan.
Articles
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Application of image-recognition techniques to automated micronucleus detection in the in vitro micronucleus assay
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Astaxanthin suppresses the malignant behaviors of nasopharyngeal carcinoma cells by blocking PI3K/AKT and NF-ÎşB pathways via miR-29a-3p
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The spectrum of TP53 mutations in Rwandan patients with gastric cancer
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Lack of in vivo mutagenicity of carbendazim in the liver and glandular stomach of MutaMice
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Low-dose radiation from A-bombs elongated lifespan and reduced cancer mortality relative to un-irradiated individuals
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The micronucleus test—most widely used in vivo genotoxicity test—
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Mechanism and regulation of DNA damage recognition in nucleotide excision repair
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Mechanisms of interstrand DNA crosslink repair and human disorders
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The health effects of radon and uranium on the population of Kazakhstan
Aims and scope
Genes and Environment is an open-access, peer-reviewed journal that aims to accelerate communications among global scientists working in the fields of genes and environment. The journal welcomes papers dealing with those topics that are relevant to the environment, such as mutagenesis and carcinogenesis, genomics and epigenetics, molecular epidemiology and genetic toxicology, and regulatory sciences.
About JEMS
The mission of the Japanese Environmental Mutagen and Genome Society (JEMS) is to discover how environmental mutagens affect all organisms, and to promote and apply this knowledge to protect human health and our environment. JEMS was founded in 1972, and since then the society has hosted annual conferences and open symposia on timely topics. The society is a member of the Asian Association of the Environmental Mutagen Societies and the International Association of Environmental Mutagenesis and Genomics Societies.
Acknowledgement and information
-Publication of Genes and Environment is partly supported by the Japan Society of Promotion of Science Grant-in-Aid for Publication of Scientific Research Results, aka KAKENHI. (Grant Number 17HP2002).
-Genes and Environment archive of papers published before 2015 are available at: https://www.jstage.jst.go.jp/browse/jemsge
Genes and Environment is an official journal of The Japanese Environmental Mutagen and Genome Society (JEMS).
2022 Citation Impact
1.7 - 2-year Impact Factor
1.9 - 5-year Impact Factor
0.563 - SNIP (Source Normalized Impact per Paper)
0.537 - SJR (SCImago Journal Rank)
2023 Speed
7 days submission to first editorial decision for all manuscripts (Median)
91 days submission to accept (Median)
2023 Usage
314,686 downloads
181 Altmetric mentions