Korelacija topografske lokalizacije i kliničkih manifestacija u cilju indikacija za hirurško liječenje osteohondroma.
In: Scripta Medica, Jg. 47 (2016-04-01), Heft 1, S. 16-20
Online
academicJournal
Zugriff:
Introduction. Osteochondroma is the most common type of benign bone tumor which appears in two forms, sessile and pedunculated. It accounts for 50% of all benign tumors of bone tissue with a double tendency towards male population. It is covered by cartilage cap of different thickness. The thickness of the cap over 30 mm can indicate a malign transformation into the secondary chondrosarcoma. Aim of the study. Determine if there is a correlation between epidemic characteristics of the patients, pathohistologic characteristics, thickness of the cartilage cap and biological behavior of the tumor. Patientsand methods. Cross-sectional study included 37 patients which were diag nosed with osteochondroma in the period of 12 months, during the year 2014, at the Institute for pathology of Medical Faculty in Belgrade. The patients' age, sex, localization, clinical manifestation and length of the case history were descriptively determined. The thickness of the cartilage cap was morphometrically determinedon pathohistologic devices of re-sectioned tumors. Out of 37 patients with diagnosed osteochondroma, 3 of them (8%) had malign alteration of the cartilage cap. The thickness of the cartilage cap in all the 3 of them was over 30 mm, ranging from 68-120 mm. Relapse was found in 3 patients (8%). Discussion. The highest importance of this lesion comes from the fact that it is the most common bone tumor with high incidence and possibility for malign transformation of the cartilage cap into secondary chondrosarcoma which makes this tumor interesting for medical staff at the clinic and pathologists. Conclusion. The width of a cartilage cap, in correlation with clinical and radiology parameters, is a significant predictive parameter of biological behavior of osteochondroma. [ABSTRACT FROM AUTHOR]
Uvod. Osteohondrom je najčešći benigni tumor kosti koji se javlja u dva oblika, kao sesilni i kao pendularni. Čini do 50% svih benignih tumora koštanog tkiva, sa dvostrukom predilekcijom ka osobama muškog pola. Prekriven je hrskavičnom kapom različite debljine. Debljina hrskavične kape preko 30 mm može ukazivati na malignu transformaciju u sekundarni hondrosarkom. Cilj rada. Utvrditi da li postoji korelacija između epidemioloških karakteristika pacijenata, patohistoloških karateristika, debljine hrskavične kape i biološkog ponašanja tumora. Ispitanici i metode. Studija presjeka obuhvatila je 37 ispitanika kojima je u periodu od 12 mjeseci, tokom 2014. godine, na Institutu za patologiju Medicinskog fakulteta u Beogradu dijagnostikovan osteohondrom. Pacijentima je deskriptivno analizirana starost, pol, lokalizacija, kliničke manifestacije i dužina trajanja anamneze. Morfometrijski je određivana debljina hrskavične kape na patohistološkim prepara tima resekovanih tumora. Od 37 bolesnika kojima je dijagnostikovan osteohondrom, kod 3 (8%) je nastupila maligna alteracija hrskavične kape. Debljina hrskavične kape kod sva tri je bila preko 30 mm, a kretala se od 68-120 mm. Recidiv se javio kod 3 (8%) pacijenta. Diskusija. Najveći značaj ove lezije proističe iz činjenice da je to najčešći koštani tumor, velike incidencije, i mogućnost maligne transformacije hrskavične kape u sekundarni hondrosarkom čine ovaj tumor interesantnim za kliničare i patologe. Zaključak. Širina hrskavične kape u korelaciji sa kliničko-radiološkim parametrima je značajan prediktivni parametar biološkog ponašanja osteohondroma. [ABSTRACT FROM AUTHOR]
Titel: |
Korelacija topografske lokalizacije i kliničkih manifestacija u cilju indikacija za hirurško liječenje osteohondroma.
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Autor/in / Beteiligte Person: | Kunarac, Slaviša ; Aćimović, Jela ; Domuzin, Marinko ; Maran, Milorad ; Mihajlović, Slaviša |
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Zeitschrift: | Scripta Medica, Jg. 47 (2016-04-01), Heft 1, S. 16-20 |
Veröffentlichung: | 2016 |
Medientyp: | academicJournal |
ISSN: | 0350-8218 (print) |
DOI: | 10.18575/msrs.sm.s.16.03 |
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