The Long-Term Impact of Neurofeedback on Symptom Burden and Interference in Patients With Chronic Chemotherapy-Induced Neuropathy: Analysis of a Randomized Controlled Trial.
In: Journal of Pain & Symptom Management, Jg. 55 (2018-05-01), Heft 5, S. 1276-1285
Online
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Zugriff:
Context: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment and may adversely affect quality of life (QOL) for years. Objectives: We explored the long-term effects of electroencephalographic neurofeedback (NFB) as a treatment for CIPN and other aspects of QOL. Methods: Seventy-one cancer survivors (mean age 62.5; 87% females) with CIPN were randomized to NFB or to a waitlist control (WLC) group. The NFB group underwent 20 sessions of NFB where rewards were given for voluntary changes in electroencephalography. Measurements of pain, cancer-related symptoms, QOL, sleep, and fatigue were obtained at baseline, end of treatment, and one and four months later. Results: Seventy one participants enrolled in the study. At the end of treatment, 30 in the NFB group and 32 in the WLC group completed assessments; at four months, 23 in the NFB group and 28 in the WLC completed assessments. Linear mixed model analysis revealed significant group × time interaction for pain severity. A general linear model determined that the NFB group had greater improvements in worst pain (primary outcome) and other symptoms such as numbness, cancer-related symptom severity, symptom interference, physical functioning, general health, and fatigue compared with the WLC group at the end of treatment and four months (all P < 0.05). Effect sizes were moderate or large for most measures. Conclusion: NFB appears to result in long-term reduction in multiple CIPN symptoms and improved postchemotherapy QOL and fatigue. [ABSTRACT FROM AUTHOR]
Titel: |
The Long-Term Impact of Neurofeedback on Symptom Burden and Interference in Patients With Chronic Chemotherapy-Induced Neuropathy: Analysis of a Randomized Controlled Trial.
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Autor/in / Beteiligte Person: | Prinsloo, Sarah ; Lopez, Gabriel ; Cohen, Lorenzo ; Novy, Diane ; Driver, Larry ; Lyle, Randall ; Ramondetta, Lois ; Eng, Cathy ; Li, Yisheng |
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Zeitschrift: | Journal of Pain & Symptom Management, Jg. 55 (2018-05-01), Heft 5, S. 1276-1285 |
Veröffentlichung: | 2018 |
Medientyp: | academicJournal |
ISSN: | 0885-3924 (print) |
DOI: | 10.1016/j.jpainsymman.2018.01.010 |
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