Poster Presentations.
In: American Journal of Reproductive Immunology, Jg. 89 (2023-05-02), S. 74-112
Online
academicJournal
Zugriff:
Daniel Schemenauer, Dorothy K. Sojka I Loyola University Chicago, Maywood, IL, USA i B Problem b : Epidemiological studies in humans implicate maternal expression of different combinations of KIRs, which are a family of cell surface receptors that tune cellular activation status, as being predictive in pregnancy complication onset (e.g., preeclampsia) and fetal health. With these markers, placental immunocytes were identified, which include decidual macrophages and fetal Hoffbauer cells, blood NK cells and decidual NK cells, Monocytes, plasma cells, and T and B cells. The pregnancy rate in the higher GM-CSF-producing NK cell group (>=7.9%) was 65.2% (15/23), while the lower GM-CSF-producing NK cell group (<7.9%) had a significantly lower pregnancy rate of 26.7% (4/15) ( I p i < .05). CD56bright cells expressed CD54 in more than half of the cells (CD54 SP + sp cells in CD56 SP bright sp cells, 67.8% [45.3%-86.4%]) and CD56 SP dim sp cells expressed CD54 in about 10% of the cells (8.6% [5.7%-11.0%]). Among women with RPL and immune abnormalities, increased peripheral blood NK cell activity and numerical abnormalities of NK cells have been reported, as well as increased CD16 SP + sp CD56 SP dim sp cells in endometrial NK cells. [Extracted from the article]
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Poster Presentations.
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Zeitschrift: | American Journal of Reproductive Immunology, Jg. 89 (2023-05-02), S. 74-112 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1046-7408 (print) |
DOI: | 10.1111/aji.13696 |
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