Short-term and long-term outcomes in living donors for liver transplantation: Cohort study.
In: International Journal of Surgery, Jg. 84 (2020-12-01), S. 147-153
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Zugriff:
Background: Although perioperative outcomes following donor hepatectomy (DH) have been reported, little is known about the long-term outcomes in living donors of liver transplantation. The aim of this study was to investigate the short-term and long-term outcomes following DH. Methods: A total of 408 living donors who underwent DH between 1996 and 2019 were analyzed in this retrospective study, focusing on short-term outcomes with respect to the operation period (era) and the graft type, as well as long-term outcomes. Results: The overall incidence of postoperative complications was 40.4%. These included minor (30.4%), major (10.0%), and biliary (14.0%) complications. Short-term outcomes after DH slightly improved over time, and outcomes did not differ significantly between the graft types. With regards to long-term outcomes, the incidence of surgery-related complications such as keloids, incisional hernias, and mechanical bowel obstructions was 6.6% over a median follow-up of 7.2 years. In addition, some donors developed comorbidities such as lifestyle diseases and cancers during the follow-up period. Conclusions: Our study confirmed an improvement of perioperative outcomes in living donors. There was no significant association between the graft type and postoperative outcomes. Donors could develop various morbidities during long-term follow-up. Therefore, a careful perioperative management and long-term follow-up should be provided to living donors. [ABSTRACT FROM AUTHOR]
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Short-term and long-term outcomes in living donors for liver transplantation: Cohort study.
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Autor/in / Beteiligte Person: | Takagi, Kosei ; Umeda, Yuzo ; Yoshida, Ryuichi ; Watanabe, Nobuyuki ; Kuise, Takashi ; Yoshida, Kazuhiro ; Yasui, Kazuya ; Matsuda, Tatsuo ; Fujiwara, Toshiyoshi ; Yagi, Takahito |
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Zeitschrift: | International Journal of Surgery, Jg. 84 (2020-12-01), S. 147-153 |
Veröffentlichung: | 2020 |
Medientyp: | academicJournal |
ISSN: | 1743-9191 (print) |
DOI: | 10.1016/j.ijsu.2020.11.013 |
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