Enhanced recovery after low- and medium-risk liver transplantation. A single-center prospective observational cohort study.
In: International Journal of Surgery, Jg. 85 (2021), S. 46-54
Online
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Zugriff:
Background& Aims: Few studies have fully applied an enhanced recovery after surgery (ERAS) protocol to liver transplantation (LT). Our aim was to assess the effects of a comprehensive ERAS protocol in our cohort of low- and medium-risk LT patients. Methods: The ERAS protocol included pre-, intra-, and post-operative steps. During the five-year study period, 181 LT were performed in our institution. Two cohorts were identified: low risk patients (n = 101) had a laboratory model for end-stage liver disease (MELD) score of 20 points or less at the time of LT, received a liver from a donor after brain death, and had a balance of risk score of 9 points or less; medium-risk patients (n = 15) had identical characteristics except for a higher MELD score (21-30 points). In addition, we analyzed the remaining patients (n = 65) who were transplanted over the same study period separately using the ERAS protocol. Results: The low-risk cohort showed a low need for packed red blood cells transfusion (median: 0 units) and renal replacement therapy (1%), as well as a short length of stay both in the intensive care unit (13 h) and in the hospital (4 days); morbidity during one-year follow-up, and probability of surviving to one year (89.30%) and five years (76.99%) were in line with well-established reference data. Similar findings were observed in the medium-risk cohort. Conclusions: This single-center prospective observational cohort study provides evidence that ERAS is feasible and safe for low- and medium-risk LT. [ABSTRACT FROM AUTHOR]
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Enhanced recovery after low- and medium-risk liver transplantation. A single-center prospective observational cohort study.
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Autor/in / Beteiligte Person: | Rodríguez-Laiz, Gonzalo P. ; Melgar, Paola ; Alcázar-López, Cándido ; Franco-Campello, Mariano ; Martínez-Adsuar, Francisco ; Navarro-Martínez, José ; Gómez-Salinas, Luís ; Pascual, Sonia ; Bellot, Pau ; Carnicer, Fernando ; Rodríguez-Soler, María ; Palazón, José M. ; Mas-Serrano, Patricio ; Almanza-López, Susana ; Jaime-Sánchez, Francisco ; Perdiguero, Miguel ; de Santiago, Carlos ; Lozano, Teresa ; Irurzun, Javier ; Pérez, Enrique |
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Zeitschrift: | International Journal of Surgery, Jg. 85 (2021), S. 46-54 |
Veröffentlichung: | 2021 |
Medientyp: | academicJournal |
ISSN: | 1743-9191 (print) |
DOI: | 10.1016/j.ijsu.2020.12.003 |
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