Spontaneous Animal Models.
In: Arrhythmogenic RV Cardiomyopathy/Dysplasia; 2007, p69-78, 10p
Online
Buch
Zugriff:
Cardiovascular disease occurs commonly in companion animals, particularly in domestic cats and dogs [1]. Myocardial disease represents a substantial portion of these disorders, many of which closely resemble cardiomyopathies in human patients [2]. Such disorders in cat, include hypertrophic [3, 4], dilated [5], restrictive [6, 7], and arrhythmogenic right ventricular cardiomyopathies (ARVC/D) [8]. A heritable form of hypertrophic cardiomyopathy associated with a cardiac myosin binding protein C mutation has been recently reported in the Maine Coon cat breed [4]. In dogs, chronic myxomatous valve disease is the most prevalent cardiac disorder [9, 10], but cardiomyopathies occur frequently, particularly within certain medium and large-sized breeds [10]. Familial forms of dilated cardiomyopathy have been described in the Doberman Pinscher [11], Irish wolfhound [12], and Great Dane [13], and a familial form of ARVC/D has been reported in the boxer breed [14, 15]. Dysplastic conditions of the right ventricle (RV) have been described in other mammals including minks [16] and rodents. In mice, ARVC/D has been associated with mutation of the gene laminin receptor [17]. One of the authors (PF) has observed a case of ARVC/D in a primate. [ABSTRACT FROM AUTHOR]
Copyright of Arrhythmogenic RV Cardiomyopathy/Dysplasia is the property of Springer eBooks and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Spontaneous Animal Models.
|
---|---|
Autor/in / Beteiligte Person: | Markus, Frank I. ; Nava, Andrea ; Fox, Philip R. ; Basso, Cristina ; Thiene, Gaetano ; Maron, Barry J. |
Link: | |
Quelle: | Arrhythmogenic RV Cardiomyopathy/Dysplasia; 2007, p69-78, 10p |
Veröffentlichung: | 2007 |
Medientyp: | Buch |
ISBN: | 978-88-470-0489-4 (print) |
DOI: | 10.1007/978-88-470-0490-0_9 |
Sonstiges: |
|