Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms
In: Blood, Jg. 141 (2023-06-08), Heft 23, S. 2824-2840
Online
serialPeriodical
Zugriff:
•Granulocyte activation and inflammatory cytokine signaling by interferon gamma and IL-6 drive TCL progression and disease symptoms.•Jak1/2 inhibitors simultaneously target malignant T cells and inflammatory granulocytes in ITK-SYK mice and human PTCL–derived xenografts.
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Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms
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Autor/in / Beteiligte Person: | Jaeger, Amelie ; Gambheer, Sudheer Madan Mohan ; Sun, Xiaoyang ; Chernyakov, Dmitry ; Skorobohatko, Oleksandra ; Mack, Thomas ; Kissel, Sandra ; Pfeifer, Dietmar ; Zeiser, Robert ; Fisch, Paul ; Andrieux, Geoffroy ; Bräuer-Hartmann, Daniela ; Bauer, Marcus ; Schulze, Susann ; Follo, Marie ; Boerries, Melanie ; von Bubnoff, Nikolas ; Miething, Cornelius ; Hidalgo, Jose Villacorta ; Klein, Claudius ; Weber, Thomas ; Wickenhauser, Claudia ; Binder, Mascha ; Dierks, Christine |
Link: | |
Zeitschrift: | Blood, Jg. 141 (2023-06-08), Heft 23, S. 2824-2840 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 0006-4971 (print) ; 1528-0020 (print) |
DOI: | 10.1182/blood.2022015653 |
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