Spatial and molecular profiling of the mononuclear phagocyte network in classic Hodgkin lymphoma
In: Blood, Jg. 141 (2023-05-11), Heft 19, S. 2343-2358
Online
serialPeriodical
Zugriff:
•Tumor-associated MNP are diverse and spatially polarized: cDC2 colocalize with malignant HRSCs; plasmacytoid and activated DCs are excluded.•DCs, monocytes, and macrophages exist in an inflammatory niche in close proximity to HRSCs, and all express inhibitory molecules.
Titel: |
Spatial and molecular profiling of the mononuclear phagocyte network in classic Hodgkin lymphoma
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Autor/in / Beteiligte Person: | Stewart, Benjamin J. ; Fergie, Martin ; Young, Matthew D. ; Jones, Claire ; Sachdeva, Ashwin ; Blain, Alex ; Bacon, Chris M. ; Rand, Vikki ; Ferdinand, John R. ; James, Kylie R. ; Mahbubani, Krishnaa T. ; Hook, Liz ; Jonas, Nicolaas ; Coleman, Nicholas ; Saeb-Parsy, Kourosh ; Collin, Matthew ; Clatworthy, Menna R. ; Behjati, Sam ; Carey, Christopher D. |
Link: | |
Zeitschrift: | Blood, Jg. 141 (2023-05-11), Heft 19, S. 2343-2358 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 0006-4971 (print) ; 1528-0020 (print) |
DOI: | 10.1182/blood.2022015575 |
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