Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers

Kayser, Veysel

Basel: MDPI - Multidisciplinary Digital Publishing Institute, 2022

Online E-Book - 298

Zugriff:

View record at Directory of Open Access Books (Volltext)

The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody–Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint inhibitors and other closely related topics. Each paper was written by leading active research groups in their fields both from academia and industry. The book should be of interest to those scientists and researchers who develop or use biologics, biotherapeutics, biosimilars and biobetters in cancer treatment.

Titel:	Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers
Autor/in / Beteiligte Person:	Kayser, Veysel
Link:	View record at Directory of Open Access Books (Volltext)
Veröffentlichung:	Basel: MDPI - Multidisciplinary Digital Publishing Institute, 2022
Medientyp:	E-Book
Umfang:	298
ISBN:	978-3-0365-2686-7 (print) ; 978-3-0365-2687-4 (print)
DOI:	10.3390/books978-3-0365-2686-7
Schlagwort:	monoclonal antibody NSCLC immunotherapy ELISA pharmacokinetics pharmacogenetics anti-PD-1 monoclonal antibodies anti-acetylcholine receptor (AChR) antibody B cell immune checkpoint blockade immune-related adverse events (irAEs) myasthenia gravis (MG) non-small-cell lung cancer (NSCLC) nivolumab programmed cell death ligand 1 (PD-L1) T cell tetraspanins cancer Tspan8 radioimmunotherapy immune-checkpoint inhibitors LDH biomarkers Ang-2 antiangiogenic therapy in vivo imaging radio- and chemotherapy VEGF-A cancer therapy neovascularization angiogenesis tumor microenvironment colorectal cancer antibody NK cells ADCC CD133 prominin-1 gold nanoparticles antibody-drug conjugates cell penetrating peptide HIV-1 TAT active-targeting targeted delivery trastuzumab MMAE valine-citrulline affibody drug conjugates hepatic uptake DM1 dermatooncology immune checkpoints monoclonal antibodies passive immunotherapy canine B-cell lymphoma DLA-DR HLA-DR antibody-drug conjugate ADC methotrexate tumor immunity combination therapy multiple myeloma (MM) monoclonal antibodies (mAbs) antibody products B cell maturation antigens (BCMAs) bispecific T cell engagers (BiTEs®) checkpoint inhibitors 1 protein structure 2 pharmacokinetics 3 drug optimization 4 HER2-positive breast cancer metastatic disease neoadjuvant and adjuvant therapy targeted therapy acute myeloid leukemia CD123 IL3RA kinesin spindle protein inhibitor bic Book Industry Communication:M Medicine bic Book Industry Communication:K Economics, finance, business & management:KN Industry & industrial studies:KND Manufacturing industries:KNDP Pharmaceutical industries
Sonstiges:	Nachgewiesen in: Directory of Open Access Books Sprachen: English Document Type: eBook File Description: image/jpeg Language: English Rights: Attribution 4.0 International ; URL: https://creativecommons.org/licenses/by/4.0/ Notes: ONIX_20220224_9783036526867_101

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