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Membrane proteins are essential for the diverse biological functions of the cells and intercellular communication in living organisms. With the recent developments in the methodologies, the research on membrane proteins has been undergoing a major transformation. In this informative book, the biological and dynamic behaviour of membrane proteins are introduced, discussed, and reviewed by some of the leading researchers in the field. The main objective of this compendium is to present the recent research in the fundamental and advanced concepts and methodologies used for studying membrane proteins. Membrane protein purification and reconstitution, protein–lipid interaction, ion/substrate transport, conformational and functional dynamics, the interaction of infectious agents, cell death, and organelle morphology are among the topics that are covered. This reprint is intended for a broad range of novice and experienced scientists with different levels of experience, from biophysicists and biochemists to microbiologists, cell biologists, and physiologists.

Titel:	Membrane Proteins: Structure, Function and Motion
Autor/in / Beteiligte Person:	Jelokhani-Niaraki, Masoud
Link:	View record at Directory of Open Access Books (Volltext)
Veröffentlichung:	Basel: MDPI - Multidisciplinary Digital Publishing Institute, 2023
Medientyp:	E-Book
Umfang:	516
ISBN:	978-3-0365-6537-8 (print) ; 978-3-0365-6538-5 (print)
DOI:	10.3390/books978-3-0365-6538-5
Schlagwort:	band 3 red blood cells antimalarial drugs molecular docking molecular dynamics membrane mechanics flicker-noise spectroscopy neurodegeneration amyloid-beta peptides pressure wave giant unilamellar vesicles membrane protein lipid bilayer membrane mimetic potassium channels tetraalkylammonium salts protein thermal stability homo-FRET C-type inactivation binding affinity selectivity filter conformation steady-state and time-resolved fluorescence anisotropy long-chain fatty acid proton transfer purine nucleotide conductance measurements in model membranes uncoupling SARS-CoV-2 Betacoronavirus Coronaviridae transmembrane proteins pathogenesis inflammation immunity vaccines CA3-CA1 synapses NMDA AMPA systems biology multiscale modeling Schaffer collateral-CA1 synapses fatty acid anion transport proton transport ADP/ATP carrier protein mitochondrial transporter arachidonic acid long-chain fatty acids nitric oxide ferroptosis lipid peroxidation lipoxygenase structure O2 and NO● binding mechanisms 1-stearoyl-2-arachidonoyl phosphatidylethanolamine (1-SA-2-ETE-PE or SAPE) lipidomics MD simulations influenza virus fusion peptides peptide-membrane interactions membrane fusion membrane peptidoglycan efflux pump assembly resistance Pseudomonas AAA-type protease Arabidopsis thaliana FtsH metalloprotease chloroplast embryo lethal leaf variegation plastid biogenesis protein import oxidative stress lipid–protein interaction cryo-electron microscopy hydrogen–deuterium exchange mass spectrometry native mass spectrometry single-molecule Förster resonance energy transfer double electron–electron resonance angulin-1 LSR tricellulin tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells intermediate-tight epithelium HT-29/B6 cells apoptosis mitochondria Bcl-2 family Bax Bid protein–protein interaction protein oligomerization fluorescence single particle detection tetraspanins CD81 CD82 gangliosides single-molecule tracking microdomain membrane diffusion fluorescence microscopy integral membrane protein membrane lipid structure function oligomeric state cryo-EM advanced mass spectrometry membrane mimetic systems HMG-CoA reductase HMGR HMGR vesicle ER-HMGR domain mevalonate endoplasmic reticulum OSER high-pressure freezing chemical fixation Archaerhodopsin-3 microfluidics cell-free gene expression cytochrome b5 reductase cytochrome b5 superoxide anion radical electron transfer protein intrinsic dynamics odorant receptor chemosensory membrane traffic heterologous expression mitochondrial carriers uncoupling proteins ADP/ATP carrier membrane protein structure and function regulation and mechanism of proton transport membrane protein oligomerization ATP synthesis biphasic proton transport model alternating access mechanism reactive oxygen species control chloroplast-targeting pathways chloroplast outer membrane proteome signal anchored protein tail anchored protein β-barrel protein β-signal chloroplast transit peptide TOC complex AKR2 OEP80 ATP-binding cassette (ABC) transporter multidrug and toxic compound extrusion (MATE) transporter monosaccharide transporter (MST) sucrose transporter (SUT) amino acid transporter detoxification nutrient transport stress adaptation proton gradient cellular pH small HSP membrane chaperone membrane fluidity stress response bic Book Industry Communication:G Reference, information & interdisciplinary subjects:GP Research & information: general bic Book Industry Communication:R Earth sciences, geography, environment, planning:RG Geography
Sonstiges:	Nachgewiesen in: Directory of Open Access Books Sprachen: English Document Type: eBook File Description: image/jpeg Language: English Rights: Attribution 4.0 International ; URL: https://creativecommons.org/licenses/by/4.0/ Notes: ONIX_20230307_9783036565378_41

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Membrane Proteins: Structure, Function and Motion