Value of albumin-related ratios in predicting the risk of death in patients with hepatitis B virus-related acute-on-chronic liver failure
In: Linchuang Gandanbing Zazhi, Jg. 39 (2023), Heft 11, S. 2580-2587
Online
academicJournal
Zugriff:
Objective To investigate and compare the value of albumin-related ratios [total bilirubin-to-albumin ratio (TAR), creatinine-to-albumin ratio (CAR), prothrombin time-international normalized ratio-to-albumin ratio (IAR), neutrophil count-to-albumin ratio (NAR), and red blood cell distribution width-to-albumin ratio (RAR)] in predicting the short-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). Methods A retrospective analysis was performed for 354 patients with HBV-ACLF who were admitted to Department of Infectious Diseases, The Affiliated Hospital of Southwest Medical University, from June 2017 to February 2022, and according to their prognosis at 3 months of follow-up, they were divided into survival group (n=272) and death group (n=82). Related indices were recorded for all patients, including age, sex, complications, and the results of routine blood test, liver function, and coagulation for the first time after admission, and albumin-related ratios and Model for End-Stage Liver Disease (MELD) score were calculated. The t-test was used for comparison of normally distributed continuous data between groups, and the Mann-Whitney U test was used for comparison of non-normally distribution continuous data between groups; the chi-square test was used for comparison of categorical data between groups. The Spearman correlation test was used to investigate the correlation between albumin-related ratios and MELD score. The Logistic regression analysis was used to explore the association of MELD score, TAR, CAR, IAR, NAR, and RAR with poor prognosis. The area under the ROC curve (AUC) was used to as sess the accuracy of albumin-related ratios and MELD score in predicting the short-term prognosis of HBV-ACLF patients, and the De-Long test was used for the comparison of AUC. Results Compared with the death group, the survival group had significantly lower MELD score (Z=-8.071, P
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Value of albumin-related ratios in predicting the risk of death in patients with hepatitis B virus-related acute-on-chronic liver failure
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Autor/in / Beteiligte Person: | Yu, ZENG |
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Zeitschrift: | Linchuang Gandanbing Zazhi, Jg. 39 (2023), Heft 11, S. 2580-2587 |
Veröffentlichung: | Editorial Department of Journal of Clinical Hepatology, 2023 |
Medientyp: | academicJournal |
ISSN: | 1001-5256 (print) |
DOI: | 10.3969/j.issn.1001-5256.2023.11.011 |
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