The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes
In: Журнал органічної та фармацевтичної хімії, Jg. 21 (2023), Heft 4, S. 36-42
Online
academicJournal
Zugriff:
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic procedures for obtaining nitriles, amines and carboxylic acids containing in their structure small saturated cyclic rings of cyclopropane or cyclobutane and a dimethylphosphine oxide fragment, which are popular in drug design, have been developed.
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The Synthesis of Functionalized Dimethylphosphinoyl Cyclopropanes and Cyclobutanes
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Autor/in / Beteiligte Person: | Aleksandrova, Anastasiia M. ; Cherednichenko, Alona S. ; Rassukana, Yuliya V. |
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Zeitschrift: | Журнал органічної та фармацевтичної хімії, Jg. 21 (2023), Heft 4, S. 36-42 |
Veröffentlichung: | National University of Pharmacy (Kharkiv, Ukraine), 2023 |
Medientyp: | academicJournal |
ISSN: | 2308-8303 (print) ; 2518-1548 (print) |
DOI: | 10.24959/ophcj.23.299237 |
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