In the differential diagnosis of sepsis and hemophagocytic lymphohistiocytosis, procalcitonin and C-reactive protein (CRP) may be as determinant as ferritin
In: Dicle Medical Journal, Jg. 49 (2022), Heft 2, S. 297-307
Online
academicJournal
Zugriff:
Background: Hemophagocytic lymphohistiocytosis (HLH) and sepsis frequently appear as overlapping diagnoses in intensive care units. It is necessary to distinguish HLH, which has a very high mortality, from sepsis. In this study, we wanted to draw attention to the potential of procalcitonin (PCT) and C-Reactive Protein (CRP) as a marker like ferritin in differential diagnosis. Thus, HLH can be diagnosed as early as possible and the necessary aggressive immunosuppressive therapy can be added to the existing treatment. Methods: All of the patients in the sepsis clinic who meet the HLH criteria Group HLH; patients not meeting the HLH criteria were defined as Group non-HLH. Files of all patients were reviewed in regard to HLH diagnosis criteria and Hscore. Results: There were 16 patients in Group HLH and 15 in Group non-HLH. CRP and PCT levels were significantly lower (p: 0.007 and p
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In the differential diagnosis of sepsis and hemophagocytic lymphohistiocytosis, procalcitonin and C-reactive protein (CRP) may be as determinant as ferritin
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Autor/in / Beteiligte Person: | Oto, Arzu ; Erdogan, Seher ; Akbayram, Sinan ; Bosnak, Mehmet |
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Zeitschrift: | Dicle Medical Journal, Jg. 49 (2022), Heft 2, S. 297-307 |
Veröffentlichung: | Dicle University Medical School, 2022 |
Medientyp: | academicJournal |
ISSN: | 1300-2945 (print) ; 1308-9889 (print) |
DOI: | 10.5798/dicletip.1128911 |
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