Glomerular filtration rate in children with juvenile idiopathic arthritis
In: Zdorovʹe Rebenka, Jg. 17 (2022), Heft 1, S. 1-6
Online
academicJournal
Zugriff:
Today, it is proved that kidney injury in children with juvenile idiopathic arthritis (JIA) is characterized by a subclinical course and most often remains undiagnosed. One of the main methods to diagnose kidney lesions is determination of estimated glomerular filtration rate (eGFR). The aim of the study was to determine the most optimal method for eGFR evaluation in children with JIA by comparing different calculation methods based on serum creatinine (original Schwartz formula, Counahan-Barratt formula), serum cystatin C (cystatin C-based equation and Hoek formula). Materials and methods. Eighty children with JIA were examined. Serum creatinine level was determined twice (first and third month of study) by the colorimetric kinetic Jaffe reaction, serum cystatin C concentration was evaluated once, in the third month of the study by enzyme immunoassay. We used methods of variation statistics. Results. Parameters of eGFR by cystatin C-based equation 2012 compared to the original Schwartz formula and Counahan-Barratt formula amplified the rate of eGFR disorders by 81.3 % (p < 0.001) and 47.3 % (p < 0.001) in the first month of the study and by 81.3 % (p < 0.001) and 55.0 % (p
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Glomerular filtration rate in children with juvenile idiopathic arthritis
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Autor/in / Beteiligte Person: | Borysova, T.P. ; Samsonenko, S.V. |
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Zeitschrift: | Zdorovʹe Rebenka, Jg. 17 (2022), Heft 1, S. 1-6 |
Veröffentlichung: | Zaslavsky O.Yu., 2022 |
Medientyp: | academicJournal |
ISSN: | 2224-0551 (print) ; 2307-1168 (print) |
DOI: | 10.22141/2224-0551.17.1.2022.1484 |
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