Pancreatic Cancer-Secreted Proteins: Targeting Their Functions in Tumor Microenvironment
In: Cancers, Jg. 15 (2023-10-01), Heft 19, S. 4825-4825
Online
academicJournal
Zugriff:
Pancreatic Ductal Adenocarcinoma (PDAC) is a ravaging disease with a poor prognosis, requiring a more detailed understanding of its biology to foster the development of effective therapies. The unsatisfactory results of treatments targeting cell proliferation and its related mechanisms suggest a shift in focus towards the inflammatory tumor microenvironment (TME). Here, we discuss the role of cancer-secreted proteins in the complex TME tumor-stroma crosstalk, shedding lights on druggable molecular targets for the development of innovative, safer and more efficient therapeutic strategies.
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Pancreatic Cancer-Secreted Proteins: Targeting Their Functions in Tumor Microenvironment
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Autor/in / Beteiligte Person: | Anna Lisa Cammarota ; Falco, Antonia ; Basile, Anna ; Molino, Carlo ; Chetta, Massimiliano ; D’Angelo, Gianni ; Marzullo, Liberato ; Margot De Marco ; Maria Caterina Turco ; Rosati, Alessandra |
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Zeitschrift: | Cancers, Jg. 15 (2023-10-01), Heft 19, S. 4825-4825 |
Veröffentlichung: | MDPI AG, 2023 |
Medientyp: | academicJournal |
ISSN: | 1519-4825 (print) ; 2072-6694 (print) |
DOI: | 10.3390/cancers15194825 |
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