Gastrointestinal Symptom-Free Multiple Lymphomatous Polyposis: An Atypical Case Presentation of Mantle Cell Lymphoma
In: Case Reports in Gastroenterology, Jg. 18 (2024), Heft 1, S. 313-317
Online
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Zugriff:
Introduction: Mantle cell lymphoma (MCL), a rare non-Hodgkin’s lymphoma, exhibits a genetic translocation causing CCND1 gene overexpression, affecting 5% of NHL cases, predominantly in males aged 60–70. Typically diagnosed with advanced symptoms, MCL involves widespread disease and organ spread, being aggressive and incurable with a 1.8–9.4-year average survival. Optimal treatment depends on disease aggressiveness and age. Multiple lymphomatous polyposis (MLP), a rare MCL subtype in the GI tract, is usually present with GI symptoms. Case Presentation: A 71-year-old woman was diagnosed with asymptomatic MLP during MCL staging who underwent thoracentesis due to large right pleural effusion and significant axillary lymphadenopathy and was treated with a chemotherapy regimen of rituximab/cytarabine and later transitioned to bendamustine/rituximab. This patient eventually underwent a bone marrow biopsy and later a bone marrow transplant. Conclusion: We present a unique case of asymptomatic MLP, emphasizing the importance of early detection for the poor prognosis of MLP with a mean survival of less than 3 years.
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Gastrointestinal Symptom-Free Multiple Lymphomatous Polyposis: An Atypical Case Presentation of Mantle Cell Lymphoma
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Autor/in / Beteiligte Person: | Desai, Rahil ; Khazey, Katherine ; Sandhu, Hasnoor ; Makar, Peter ; Randhawa, Navkiran ; Khalyfa, Ahamed ; Khan, Mahnoor ; Yarbrough, Alex ; Spyratos, Tilemahos |
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Zeitschrift: | Case Reports in Gastroenterology, Jg. 18 (2024), Heft 1, S. 313-317 |
Veröffentlichung: | Karger Publishers, 2024 |
Medientyp: | academicJournal |
ISSN: | 1662-0631 (print) |
DOI: | 10.1159/000539288 |
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