Human Papillomavirus Infections and Associated Cancers
In: Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Jg. 17 (2012), Heft 3, S. 93-102
Online
academicJournal
Zugriff:
Human papillomavirus types are the main tumor viruses in humans. High-risk human papillomavirus types, also called oncogenic human papillomaviruses, have been shown to be associated with cervical cancer, which is the leading cause of cancer mortality among women worldwide. High-risk human papillomavirus types are also associated with other anogenital cancers, and a subgroup of head and neck cancers. In addition, several studies have reported human papillomavirus types to be associated with some of the breast, lung, skin, and colon cancers. The proof that human papillomaviruses have a role in human oncogenesis has allowed the development of preventative and therapeutic strategies purposed at reducing the incidence and mortality rate of associated cancers. This article summarizes the main steps of the human papillomavirus life cycle and the functions of the viral proteins, and draws attention to carcinogenic mechanisms. In addition, this study presents a brief analysis of researches on cancer that were definitely or possibly associated with human papillomavirus and current information on prophylactic and therapeutic vaccine strategies against human papillomavirus infections and related cancers.
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Human Papillomavirus Infections and Associated Cancers
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Autor/in / Beteiligte Person: | Fatih, ŞAHİNER ; Ramazan, GÜMRAL |
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Zeitschrift: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Jg. 17 (2012), Heft 3, S. 93-102 |
Veröffentlichung: | Bilimsel Tip Yayinevi, 2012 |
Medientyp: | academicJournal |
ISSN: | 1300-932X (print) |
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