NIR light-activated nanocomposites combat biofilm formation and enhance antibacterial efficacy for improved wound healing
In: Communications Chemistry, Jg. 7 (2024), Heft 1, S. 1-10
Online
academicJournal
Zugriff:
Abstract Nanoparticle-based therapies are emerging as a pivotal frontier in biomedical research, showing their potential in combating infections and facilitating wound recovery. Herein, selenium-tellurium dopped copper oxide nanoparticles (SeTe-CuO NPs) with dual photodynamic and photothermal properties were synthesized, presenting an efficient strategy for combating bacterial infections. In vitro evaluations revealed robust antibacterial activity of SeTe-CuO NPs, achieving up to 99% eradication of bacteria and significant biofilm inhibition upon near-infrared (NIR) irradiation. Moreover, in vivo studies demonstrated accelerated wound closure upon treatment with NIR-activated SeTe-CuO NPs, demonstrating their efficacy in promoting wound healing. Furthermore, SeTe-CuO NPs exhibited rapid bacterial clearance within wounds, offering a promising solution for wound care. Overall, this versatile platform holds great promise for combating multidrug-resistant bacteria and advancing therapeutic interventions in wound management.
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NIR light-activated nanocomposites combat biofilm formation and enhance antibacterial efficacy for improved wound healing
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Autor/in / Beteiligte Person: | Ullah, Irfan ; Shahin Shah Khan ; Ahmad, Waqar ; Liu, Luo ; Rady, Ahmed ; Aldahmash, Badr ; Yu, Yingjie ; Wang, Jian ; Wang, Yushu |
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Zeitschrift: | Communications Chemistry, Jg. 7 (2024), Heft 1, S. 1-10 |
Veröffentlichung: | Nature Portfolio, 2024 |
Medientyp: | academicJournal |
ISSN: | 2399-3669 (print) |
DOI: | 10.1038/s42004-024-01215-1 |
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