Post-COVID syndrome: status of carbohydrate metabolism in patients with hypertension and stable ischemic heart disease
In: Mìžnarodnij Endokrinologìčnij Žurnal, Jg. 20 (2024), Heft 1, S. 25-32
Online
academicJournal
Zugriff:
Background. Post-COVID syndrome is associated with a wide range of chronic symptoms or conditions. Coronavirus disease 2019 (COVID-19) causes metabolic disorders such as hyperglycemia, insulin resistance. Insulin-like growth factor 1 (IGF-1) is associated with an impaired glucose tolerance and a higher risk of developing type 2 diabetes. Currently, the study of molecules regulating carbohydrate metabolism as potential biomarkers of post-COVID syndrome and targets for therapeutic influence is relevant. The purpose of the study was to assess the level of IGF-1 and its relationship with regulation of carbohydrate metabolism, as well as the dynamics of the evaluated indicators under the influence of drug treatment in patients with hypertension and stable coronary heart disease who suffered from COVID-19. Materials and methods. Fifty-five patients who had a mild and moderate COVID-19 were included in the study; their average age was 55.87 [40; 75] years. The results of routine laboratory tests were registered and analyzed. The content of insulin and IGF-1 was assessed by enzyme immunoassay. The HOMA-IR was calculated. Results. In patients with a moderate COVID-19 compared to those with a mild one, a significant decrease in the level of IGF-1 (р = 0.008) was found against the background of increased reference values of glucose, insulin, and HOMA-IR (р
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Post-COVID syndrome: status of carbohydrate metabolism in patients with hypertension and stable ischemic heart disease
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Autor/in / Beteiligte Person: | Kuryata, O.V. ; Mytrokhina, O.S. ; Kushnir, Yu.S. ; Stadnyk, O.I. |
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Zeitschrift: | Mìžnarodnij Endokrinologìčnij Žurnal, Jg. 20 (2024), Heft 1, S. 25-32 |
Veröffentlichung: | Zaslavsky O.Yu., 2024 |
Medientyp: | academicJournal |
ISSN: | 2224-0721 (print) ; 2307-1427 (print) |
DOI: | 10.22141/2224-0721.20.1.2024.1354 |
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