Clinical, laboratory, and radiological characteristics of COVID-19-infected children admitted to pediatric intensive care unit: a single-center experience
In: Beni-Suef University Journal of Basic and Applied Sciences, Jg. 10 (2021), Heft 1, S. 1-7
Online
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Zugriff:
Abstract Background During the second wave of COVID-19, there is an increasing incidence of reported cases in children compared to the early wave. Data on the clinical and laboratory characteristics of COVID-19 in children are evolving, and reports on the characteristics and outcomes of severe COVID-19 in children are still under evaluation. We aimed to describe the clinical, laboratory, and radiological characteristics and outcomes of children with COVID-19 infection admitted to the pediatric intensive care unit (PICU). Results The study included 27 children with COVID-19 infection. Fever, respiratory, and gastrointestinal (GIT) symptoms were predominant presenting symptoms in our patients. The median age of our patients was 9 months (2 m–12 years). Comorbidity was reported in 59.3%. The typical laboratory findings were leukocytosis, lymphopenia, elevated C-reactive proteins levels, and elevated d-dimer levels. The most frequent radiological findings were ground-glass opacities in 100% of patients and bilateral findings in 96%, while cardiomegaly was found in 44% of patients. The multisystem inflammatory syndrome was reported in 33% of patients with GIT symptoms were the most frequent presenting symptoms. Myocarditis was reported in 22% of patients. The mortality rate in this cohort was 14.8%. On multivariate analysis, the only predictor of mortality was the development of MIS-C. Conclusions COVID-19 is more severe in children with comorbid conditions. Fever, respiratory and gastrointestinal (GIT) symptoms were predominant presenting symptoms. MIS-C is of increasing concern in children with high mortality rates.
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Clinical, laboratory, and radiological characteristics of COVID-19-infected children admitted to pediatric intensive care unit: a single-center experience
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Autor/in / Beteiligte Person: | Heba Mostafa Ahmed ; Rehab Muhammad Abd El Kareem ; Faten Mohamed Ali ; Ahmed Reda Sayed ; Yasmen Awadalh Mohamed |
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Zeitschrift: | Beni-Suef University Journal of Basic and Applied Sciences, Jg. 10 (2021), Heft 1, S. 1-7 |
Veröffentlichung: | SpringerOpen, 2021 |
Medientyp: | academicJournal |
ISSN: | 2314-8543 (print) |
DOI: | 10.1186/s43088-021-00168-x |
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