Treatment of Pneumocystis jirovecii Pneumonia with Caspofungin and Clindamycin: An HIV Patient and Literature Review
In: Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Jg. 29 (2024), Heft 1, S. 139-144
Online
academicJournal
Zugriff:
The first-line treatment for Pneumocystis jirovecii pneumonia (PCP) is trimethoprim-sulfamethoxazole (TMP-SMZ). However, some cases require alternative agents due to the side effects of TMP-SMZ. Treatment with TMP-SMZ was initiated in an HIV-positive patient with microbiologically confirmed PCP, who presented with acute renal failure on admission. On the third day of treatment, TMP-SMZ was discontinued due to worsening renal function. Subsequently, clindamycin was initiated in combination with caspofungin. Although caspofungin-based therapies were shown to be effective against Pneumocystis in animal models, clinical experience in humans is limited. The patient was treated successfully with clindamycin combined with caspofungin.
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Treatment of Pneumocystis jirovecii Pneumonia with Caspofungin and Clindamycin: An HIV Patient and Literature Review
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Autor/in / Beteiligte Person: | Gül Ruhsar, YILMAZ ; Onur, KAYA ; Ahmet Çağkan, İNKAYA ; Onur, ÜNAL ; Esra NURLU, TEMEL ; Füsun Zeynep, AKÇAM ; Emel SESLİ, ÇETİN ; Barış, OTLU ; Serhat, ÜNAL |
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Zeitschrift: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Jg. 29 (2024), Heft 1, S. 139-144 |
Veröffentlichung: | Bilimsel Tip Yayinevi, 2024 |
Medientyp: | academicJournal |
ISSN: | 2024-0198 (print) ; 1300-932X (print) |
DOI: | 10.5578/flora.202401981 |
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