Thalamic stimulation modulated neural oscillations in central post-stroke pain: A case report
In: Heliyon, Jg. 10 (2024), Heft 12, S. e32535-
Online
academicJournal
Zugriff:
The characterization of neural signatures within the somatosensory pathway is essential for elucidating the pathogenic mechanisms of central post-stroke pain (CPSP) and developing more effective treatments such as deep brain stimulation (DBS). We explored the characteristics of thalamic neural oscillations in response to varying pain levels under multi-day local field potential (LFP) recordings and examined the influences of continuous DBS on these thalamic activities. We recorded LFPs from the left ventral posterolateral thalamus (VPL) of a patient with CPSP in the resting state under both off- and on-stimulation conditions. We observed significant differences in the power spectral density (PSD) of different pain levels in the delta, theta and gamma frequency bands of the left VPL; 75Hz DBS significantly increased the PSD of delta and decreased the PSD of low-beta, while 130Hz DBS significantly reduced the PSD of theta and low-beta. Thalamic stimulation modulated the neural oscillations related to pain, and the changes in neural activities in response to stimulation could serve as quantitative indicators for pain relief.
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Thalamic stimulation modulated neural oscillations in central post-stroke pain: A case report
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Autor/in / Beteiligte Person: | Niu, Qiyu ; Lin, Zhengyu ; Xu, Wenying ; Hu, Kejia ; Nie, Yingnan ; Li, Dianyou ; Wang, Shouyan |
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Zeitschrift: | Heliyon, Jg. 10 (2024), Heft 12, S. e32535- |
Veröffentlichung: | Elsevier, 2024 |
Medientyp: | academicJournal |
ISSN: | 2405-8440 (print) |
DOI: | 10.1016/j.heliyon.2024.e32535 |
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